Secondary Cardiovascular Prevention After Stroke in 2024

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Therapeutics Decision-Making Examination
Alcohol

Elimination or reduction in alcohol consumption in both men and women.

Drugs

Intravenous drug users encouraged to stop

Glycemic control

Aim for HbA1c to be less than 7%. For this, Metformin combined with a glucagon-like peptide-1 agonist (GLP-1 agonist) or a sodium-glucose cotransporter 2 inhibitor (SGLT-2 inhibitor) are recommended.

Hyperlipidemia

Aftern non embolic stroke, prescribe atorvastatin 80 mg per day, if low-density lipoprotein cholesterol level is greater than 100 mg per dL; in high-risk patients, consider adding ezetimibe and proprotein convertase subtilisin/kexin type 9 inhibitor to lower the stroke risk.

Hypertension

Lower blood pressure to less than 130/80 mm Hg

Hypertriglyceridemia

When triglycerides are 135 to 499 mg per dL in patients already taking a moderate- or high-intensity statin, consider adding icosapent ethyl

Nutrition

Mediterranean-style diet, consider reducing sodium to 1 g per day.

Obesity

Encourage weight loss.

Physical activity

Moderate-intersity exercise for 10 minutes four days a week or 20 minutes intense exercise activity two day a week.

Smoking

Encourage to stop use

Stimulants use

Encourage to stop use